Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

Name: Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Author: Meinhard Kieser

Meinhard Kieser

Springer Nature Switzerland AG

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This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.

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